4-1BBL (CD137L) Proteins

4-1BBL (CD137L) Human recombinant proteins are validated for use in the following applications: Functional Assay, ELISA, Western Blot, Blocking Assay and Immunohistochemistry. These proteins are expressed in E. coli. Available Product Grades: Animal-Free and RUO. Gibco and Invitrogen... 4-1BBL (CD137L) Human recombinant proteins are validated for use in the following applications: Functional Assay, ELISA, Western Blot, Blocking Assay and Immunohistochemistry. These proteins are expressed in E. coli. Available Product Grades: Animal-Free and RUO. Gibco and Invitrogen proteins are some of the most frequently... 4-1BBL (CD137L) Human recombinant proteins are validated for use in the following applications: Functional Assay, ELISA, Western Blot, Blocking Assay and Immunohistochemistry. These proteins are expressed in E. coli. Available Product Grades: Animal-Free and RUO. Gibco and Invitrogen proteins are some of the most frequently published proteins. 4-1BBL (CD137L) Protein have been referenced in 4 publications which can be found in our reference library. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 4 proteins, including biologically active options. Not finding the exact protein, grade or size needed?... 4-1BBL (CD137L) Human recombinant proteins are validated for use in the following applications: Functional Assay, ELISA, Western Blot, Blocking Assay and Immunohistochemistry. These proteins are expressed in E. coli. Available Product Grades: Animal-Free and RUO. Gibco and Invitrogen proteins are some of the most frequently published proteins. 4-1BBL (CD137L) Protein have been referenced in 4 publications which can be found in our reference library. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 4 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily. CD137L is a co-stimulatory molecule that is expressed on antigen presenting cells (DCs, monocytes/macrophages, B cells) and is upregulated upon activation. Its receptor, CD137/4-1BB, is found on a variety of cells, including inflamed endothelial cells, where its expression enhances extravasation of CD137L expressing monocytes. Activated T cells also express CD137, and engagement with CD137L enhances T cell proliferation, IL-2 secretion, survival, and cytotoxic activity. CD137L is also expressed on a majority of B-cell lymphomas, including mantle cell lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma (but it is lacking on Hodgkin lymphoma and T-cell lymphoma). CD137L is also expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interactions.

Synonyms

4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9

4-1BBL (CD137L) Proteins

Protein Information

Synonyms

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